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Why can’t I get pregnant? The top 10 reasons you’re struggling to conceive

  • Writer: Gail Madalena
    Gail Madalena
  • Jul 18, 2024
  • 8 min read

Updated: Jan 27

If you’ve been trying for a baby for a while with no success, you’ve probably asked yourself why can’t I get pregnant? For some people it all happens so easily, while others face month after month of continued disappointment. It’s important to know that you are not alone in your struggles. In fact, it’s estimated that sub-fertility affects a whopping 1 in 7 couples in the UK, with global fertility rates dropping by over a half in the last 50 years.


Infertility is considered when a couple has failed to conceive after 1 year of having regular unprotected sex. Unfortunately, causes aren’t always clear cut, it’s often multifactorial and can affect both partners. These factors can range from simple, fixable things such as missed ovulation windows or poor lifestyle choices, to more complicated issues such as structural damage or unexplained infertility.


Let’s take a look at the top 10 factors that could be causing problems.


1. Ovulatory disorders 

Ovulation is a crucial step in the process of conception. We need an egg to be released by the ovaries in order to get pregnant, therefore if there’s a problem within this process we will most definitely run into difficulties.  Ovulatory dysfunction counts for approximately 25% of all cases of infertility. It can be affected by a whole host of things, including:


  • Stress

  • Extended time on birth control

  • Being under or overweight

  • An imbalance of hormones which can have a direct impact on your cycles

  • Conditions such as PCOS, hypothyroidism & hyperprolactinemia

  • Premature ovarian failure

  • Deterioration of egg quality and quantity – most commonly associated with age


Any of the above can result in sporadic ovulation or an absence of ovulation all together (anovulation). This manifests as irregular periods, no period at all or abnormal bleeding patterns. With all this going on it can be extremely difficult to know when it’s the best time to have intercourse when trying for a baby. The key here is to address the underlying cause of your ovulatory disorder, which can range from anything from poor diet and lifestyle, genetic links and the environment you surround yourself in. This is where working with a nutritional therapist can become really beneficial, as we work to uncover the root cause of your issues.

It’s also worth regularly tracking your cycles to pick up on any patterns and identify if and when you ovulate. Try to have sex every other day throughout your cycle to ensure you’re hitting ovulation when it does happen.


2. Tubal damage

Tubal damage counts for 20% of all cases of infertility. Pelvic inflammatory disease (PID), commonly contracted via sexually transmitted microorganisms such as chlamydia, is a leading cause of tubal infertility.

Endometriosis can be another factor. This is where tissue similar to the lining of the womb grows in other places such as fallopian tubes or the ovaries. Endometriosis affects more than 10%-15% of women who are of childbearing age. It causes pelvic adhesions, distorted anatomy and ovarian or tubal damage. This can also have a knock-on effect in the ovulatory process.


If fallopian tubes have become blocked or damaged, then surgery is an option to correct this, or help the egg to pass through. It is however dependent on the extent of the initial damage. PID is partly preventable and endometriosis can be minimised and managed through diet and lifestyle.


3. Factors in the male causing infertility

Male infertility is on the rise, with approximately 30% of all infertility cases being due to male factors. 21st Century living and Western diets have seen a dramatic impact on sperm parameters, with increasingly lower sperm counts, poorer motility (movement) or abnormal shapes and sizes (morphology).

While many cases can be improved via diet and lifestyle, unfortunately some problems men are born with. Structural issues such as testicular damage, undescended testicles or blockages due to varicoceles can fundamentally inhibit or reduce sperm production. A urologist or testicular scan can investigate these issues further and suggest a treatment plan, which may include surgery.


As with women, infections can also be a common problem for men. A semen culture is worth having when struggling to conceive to rule this out, as it can be a simple fix by treatment with antibiotics. Hormonal imbalance can also wreak havoc on male fertility. Low testosterone levels can reduce sperm production and lower libido. While testosterone supplementation, which many men take to build muscle, can actually further damage the quality of sperm.

An increase in temperature can also have a significant impact of semen production. Any activity that increases the temperature of the scrotal area should be avoided when trying to conceive. This includes sauna’s, cycling, sitting for long periods of time, working with a laptop over the groin and wearing tight clothing.  An elevated temperature can result in DNA damage and increase in free radicals, which leads to reduced functional competence and structure of sperm.


4. Too much exercise

While exercise can definitely have positive outcomes on fertility, over exercise or intensive forms of exercise can be detrimental to both men and women. Maintaining a BMI of 18-25 is the ideal for successful pregnancy, anything below 18 can inhibit conception. In women, over exercise can cause hypothalamic suppression, disrupting hormones and causing problems with ovulation. In men, moderate exercise can increase sperm production however excessive exercise can have the opposite effect. In both sexes intense exercise can increase cortisol levels, up-regulate our sympathetic nervous system and generate harmful free radicals.

Strength training, yoga, gentle jogging, swimming and regular walking are all great options for gradual weight loss or maintaining a healthy weight.


5. Lack of crucial vitamins & minerals 

Micronutrient status affects the capacity to conceive and support a pregnancy through to birth. In particular, your body needs sufficient levels of vitamins B, C, D and E, as well as minerals including iron, zinc, selenium, choline, iodine, COQ10 and magnesium. These nutrients are crucial for supporting menstruation and ovulation, thyroid function, energy production, immune function and egg and sperm quality and maturation.

What do these nutrients do?


B Vitamins  – helps promote egg & sperm health, lowers risk of ovulatory infertility. Having higher levels of B12 & folate may enhance fertility chances when undergoing IVF.


Folic acid/Folate – supplementation prior to pregnancy can increase chances of conception, improve success rates of fertility treatments and decrease neural tube defects in the baby.


Vitamin C – essential for hormone production and ovulation. Its antioxidant qualities protect sperm DNA and improve other semen parameters.


Vitamin D – can increase the likelihood of reaching full-term pregnancy and reduces chances of preeclampsia. Some studies have seen a link between low levels of D3 and infertility.


Vitamin E – A potent antioxidant that may promote sperm function and general reproductive health in women.


Zinc – crucial for the production of sperm, sperm motility and healthy testosterone levels. It can also support the luteal phase in women, reduce prolactin and help with fertilisation.


Magnesium – Involved in oestrogen and progesterone synthesis, deficiencies have been linked to female infertility.


Selenium – A necessary nutrient needed for the production of sperm. Supplementation can improve semen quality and sperm motility.


CoQ10 – Needed for energy production and can improve egg quality in older women as well as ovarian response to IVF. It can also have beneficial effects on sperm concentration and motility.

Omega 3 – essential for healthy hormone regulation, improves egg and sperm membranes and protects them from oxidative stress

Common factors that can deplete these nutrients include certain medications including the oral contraceptive pill, which many people take continuously for years at a time. This can also interfere with our methylation and detoxification pathways, as well as cause delayed return of our natural cycles. Our biochemical individuality can also mean some people struggle to absorb nutrients at a cellular level.


Low nutrient status can be further exacerbated by eating increased levels of processed and refined foods, saturated fats and limited consumption of fruits and vegetables, which contain high levels of antioxidants, fibre and beneficial flavonoids and polyphenols. It’s estimated that only a third of men and women are achieving the five a day fruit and vegetable target set out by the government. Multiple studies have shown following a Mediterranean diet, consisting of high levels of fruits, vegetables, wholegrains, legumes, nuts, seeds, oil and fish, with limited red meat and processed foods has the most positive outcomes for pregnancy.



Taking a high-quality prenatal supplement will also ensure you are covering all the essential nutrients needed for pregnancy. However, it’s important to remember that your diet is the key priority here. You should always consult with your GP or a qualified nutritionist when taking supplements to check for nutrient/drug interactions, correct dosing and timeframes.


6. Being overweight

There are strong links between obesity and infertility across both sexes. In women excess adipose tissue can wreak havoc on hormone health, which then disrupts ovulation and can cause irregular menstruation. It can also lower success rates of assisted reproductive techniques by affecting ovulation & response to drugs.


Obesity in men can cause erectile dysfunction, lower sperm counts, reduce semen quality and create hormonal issues. 


The closer a person is to being a healthy weight, the better their chances are for conception. Anyone with a BMI > 30, which is considered overweight, should try to lower this with regular moderate exercise and a healthy diet. 


7. Smoking and toxic load  

Studies have shown that 40% of infertile men are smokers. The number, quality and motility of sperm all decrease in smokers, meaning they are less likely to fertilise an egg.  Toxic chemicals such as nicotine, cyanide and carbon monoxide in cigarettes cause a rapid destruction of eggs in females, causing female smokers to experience menopause up to 1-4 years sooner than a non-smoker. Female smokers also have a 30% lower change of successful pregnancy via IVF. Infertility rates almost double in smokers when compared to non-smokers. 


8. Not having enough sex

In many cases the problem could be as simple as not having sex within your fertile window. When trying to conceive it’s important to track your cycle and know the day you ovulate. Your peak fertility will be approx. 5 days before ovulation and the day you ovulate, so 6 days in total. This is because in the right environment sperm can live for up to 5 days in the female reproductive system waiting for an egg. Once released from the ovary an egg can survive for 48hrs. The two combined is your fertile window, knowing when this occurs and having unprotected sex every other day in this timeframe will increase your chances of pregnancy.


9. Unexplained infertility 

Unfortunately, in many cases fertility issues just can’t be explained. This is perhaps the most frustrating of causes, where semen analysis is normal and female infertility factors have been ruled out. Unexplained infertility is thought to account for up to 25% cases in the UK.

It’s important to take into account and support even subtle factors that could be causing infertility. These could be problems with fertilisation, implantation, the uterine environment, change in egg or sperm health due to ageing and lifestyle/life load.


10.  Reproductive age

Although semen quality does indeed decline with age it’s nowhere near as dramatic as women, where infertility rates accelerate after 35 years.  In this day and age women are far more career driven and holding off thinking about having children until later in life. Unfortunately, both the quality and number of eggs decline with age, unlike a man who continues to produce sperm throughout his life. There is a 71% chance of pregnancy in women below 30, however this decreases to 41% when over 36. As a woman gets older the risks also become higher, with increased rates of miscarriage and chromosomal abnormalities.

 

What can we do to improve our outcome?

Given the vast range of causes of infertility, it’s crucial to investigate appropriately and work on personal requirements with your GP, fertility specialist or nutritional therapist.

Couples with 4 or more negative lifestyle variables, including things like smoking, high alcohol consumption, poor diet, stress, obesity, toxic exposure etc, can take up to 7 times longer to get pregnant. The good news is, we have control over all these factors. Preconception is the most impactful time – in an ideal world a couple would start making changes to their diet and lifestyle at least 3 months prior to conception. The process of making new sperm takes 86 days, with eggs taking a similar length of time to mature. If you give yourself at least 3 months of making healthy changes, both egg and sperm will be in the best possible condition and stand a higher chance of fertilisation.  It’s also important to stress diet & lifestyle changes need to come from both parties, not just the women.


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